Pampano is one of The 15 Best Places for Margaritas in Midtown East, New York.

1. Pampano

7.5
209 E 49th St (btwn 3rd Ave & 2nd Ave), New York, NY
Mexican Restaurant · Turtle Bay · 86 tips and reviews

Meghan D.Meghan Day: Amazing happy hour from 5-7 at the bar! Delicious small bites and $5 margaritas!

Belle L.Belle Lenz: Swordfish dip and hibiscus margaritas are a must. Read more.

ZenFoodsterZenFoodster: With $5 apps & $4-6 drinks M-F from 5-7pm, Pampano has one of the best HH's in midtown E! Tonight, they have FREE margaritas 'til 8pm!!

Sinigual is one of The 15 Best Places for Margaritas in Midtown East, New York.

2. Sinigual

7.2
640 Third Ave (E 41st St), New York, NY
Mexican Restaurant · Midtown East · 90 tips and reviews

Dolce Cuore E.Dolce Cuore Event Planning: Have the quacamole. The shrimp salad is phenomenal so is the bbq chicken salad is awesome. Margaritas are amazing. Go patron

Coskun C.Coskun Cavusoglu: Try the Cadillac margarita it's awesome!

Meg L.Meg L: Food is incredible, highly recommend if you're in the area. And the margaritas are amazing.

Empellón is one of The 15 Best Places for Margaritas in Midtown East, New York.

3. Empellón

8.5
510 Madison Ave (at 53rd St.), New York, NY
Mexican Restaurant · Midtown East · 40 tips and reviews

Morgan M.Morgan McKee: As a connoisseur of Tex Mex, I approve for comfort Mexican food. It’s sacrilegious to not start with guac and seven dips. Pastrami tacos and short rib make your own tacos are🔥. Layer on a few margs!

Kelsey✨Kelsey✨: Spicy cucumber margarita & octopus tacos are excellent

Yaron Z.Yaron Zakai-Or: Excellent food, wonderful margaritas and tequilas. Creative Mexican cuisine and awesome service. The tacos are outstanding, the falafel is a true surprise!

Zengo is one of The 15 Best Places for Margaritas in Midtown East, New York.

4. Zengo

7.4
622 3rd Ave (at E 40th St), New York, NY
Latin American Restaurant · Midtown East · 139 tips and reviews

Jose P.Jose Pena: Thai Shrimp Lettuce wraps where great cant forget that shaken Don Julio margarita :)

Martine B.Martine B.: The strawberry margarita is to die for! Also try the arepas and the tacos for happy hour. The downstairs room is super chill and cool

Sarina G.Sarina Gamez: Absolute best margaritas! Must try the tamarind and Zengo margarita :)

Taco Dumbo is one of The 15 Best Places for Margaritas in Midtown East, New York.

5. Taco Dumbo

7.2
19 W 52nd St, New York, NY
Taco Restaurant · Midtown East · 15 tips and reviews

Emma G.Emma Gilroy: Margaritas!

Co G.Co G: I had the vegan chorizo taco salad and it was delicious! I heard the tacos are to die for. I'm not vegan but I loved the food!! Frozen margs are also yummy!

Maya M.Maya Mhatre: Super tasty tacos and cold pressed juice margaritas 😋

The Smith is one of The 15 Best Places for Margaritas in Midtown East, New York.

6. The Smith

8.8
956 2nd Ave (at E 51st St), New York, NY
American Restaurant · Turtle Bay · 364 tips and reviews

K@rTh!kk R.K@rTh!kk ReDd!: Spiced Blood Orange Margarita's Awesome. Loved having Allagash White on Draft.. Sticky Ribs & Brick Pressed Chicken were tasty n delicious. Just ask em to put more sauce on chicken.. :)

KelleyKelley: Best drinks ever. Check out the long pour section of the drinks menu. 40 thieves and spiced peach margarita are awesome

Amy M.Amy Mixa: Spicy blood orange margarita and the jalapeño cheese grits are my favs!!!

Bliss Spa is one of The 15 Best Places for Margaritas in Midtown East, New York.

7. Bliss Spa

7.9
12 W 57th St (btwn 5th & 6th Ave), New York, NY
Spa · Midtown East · 39 tips and reviews

Eryn B.Eryn Braue: Margarita is the best for a triple oxy facial.

Katie W.Katie Welch: Margarita will clean every pore. Every. Last. Pore. My skin thanks her.

Roxanna F.Roxanna Flores: My go to once a month. Beth is the best masseuse and Lola’s facials are the best.

Tacovision is one of The 15 Best Places for Margaritas in Midtown East, New York.

8. Tacovision

8.6
244 E 53rd St, New York, NY
Mexican Restaurant · Turtle Bay · 12 tips and reviews

Brittney J.Brittney Jackson: The staff is super inviting, they have margs and mezcal, AND $3 tacos on Tuesdays. Love!

Ricardo R.Ricardo Ramirez: Great place! Do the 20/20 brunch! Definitely worth it! They use the OpenTable app for reservations.

Kelsey✨Kelsey✨: Tasty lunch option in midtown! Go for the al pastor, shrimp and Alaskan cod tacos

Uncle Charlie's is one of The 15 Best Places for Margaritas in Midtown East, New York.

9. Uncle Charlie's

7.9
139 E 45th St Fl 2 (btwn Lexington & 3rd Ave.), New York, NY
Gay Bar · Turtle Bay · 26 tips and reviews

Kent L.Kent LeVan: $3 Draft & $5 Frozen Margaritas every Monday starting @ 9pm.

Jason B.Jason Baughman-Oprică: An older crowd, but with excellent bar service. No beers on tap. Full bar and wine selection. Multi-level piano bar (evenings) and an outside patio area. 🏳️‍🌈

Amber M.Amber McKechnie: Great staff, great price drinks and good fun for all gay or straight

Allure Day Spa & Hair Design is one of The 15 Best Places for Margaritas in Midtown East, New York.

10. Allure Day Spa & Hair Design

7.8
139 E 55th St (Btwn Lexington & 3rd), New York, NY
Massage Clinic · Midtown East · 26 tips and reviews

Dawn L.Dawn Lo: Margarita is awesome with Brazilians

Heidi F.Heidi Fleming: Booked a spa day for our group of 23. They handled our large group really well. We all enjoyed our treatments, and the champagne was a nice touch.

BeautyBookedBeautyBooked: A quintessential one-stop neighborhood shop, Allure Day Spa is the perfect place for a last minute trim, wax, or mani. Read more.

The Bar Downstairs and Kitchen is one of The 15 Best Places for Margaritas in Midtown East, New York.

11. The Bar Downstairs and Kitchen

7.9
485 5th Ave (41st St, inside Andaz 5th Ave), New York, NY
Cocktail Bar · Midtown East · 82 tips and reviews

Rebecca M.Rebecca Mazza: Amazing cocktails, amazing food, and amazing service! I don't think there is a wrong thing to order here. The skirt stake is outstanding and the Dali margarita!

Santi A.Santi Amaya: Great place to come for after work cocktails (Warning, they're expensive!!). Really cool space with a great selection of interesting cocktails. Get the Penicillin

Jeff T.Jeff Tropeano: This is really one of the coolest places I've been to in my 10 years in NYC. You HAVE to go. Read more.

Grand Central Terminal is one of The 15 Best Places for Margaritas in Midtown East, New York.

12. Grand Central Terminal

9.0
87 E 42nd St (btwn Vanderbilt & Park Ave), New York, NY
Rail Station · Midtown East · 1466 tips and reviews

Jenna W.Jenna W: Zocala $6 margaritas to go. Walk in and walk out with the best after work drink

Rob H.Rob Howe: Zocalo mexican restaurant... Get the blood red margaritas to go + take on the train ride home!

WillieScrapesWillieScrapes: Huge, crowded, beautiful ceiling art and a world treasure.

Karaoke Duet 48 is one of The 15 Best Places for Margaritas in Midtown East, New York.

13. Karaoke Duet 48

8.2
304 E 48th St (btwn 1st & 2nd Ave), New York, NY
Karaoke Bar · Turtle Bay · 46 tips and reviews

Cody-Ann .Cody-Ann 👑💫: private booths, great song selection, full bar!!!

Dan D.Dan Dickinson: Play Electric Six's "Gay Bar" (code C60265). It has a completely unrelated video that will make your night.

Jessica B.Jessica Brown: Great song selection and happy hour drinks are great

Pathos Cafe is one of The 15 Best Places for Margaritas in Midtown East, New York.

14. Pathos Cafe

7.5
932 1st Ave (at 51st), New York, NY
Greek Restaurant · Turtle Bay · 5 tips and reviews

Paola V.Paola Venturini: Octopus, tuna tartar, and prosciutto and gorgonzola pizza. Sangria pitchers too.

Monday L.Monday Lisa: Nice outdoor seating but food very over priced for what it is. BF got a Cuban that looked like a 5th grader made a turkey sandwich and it was $15 🙄

Elvi R.Elvi Rod: This place is really nice a the food it's excellent!!

Jams is one of The 15 Best Places for Margaritas in Midtown East, New York.

15. Jams

8.2
1414 Avenue of the Americas (at W 57th St), New York, NY
American Restaurant · Midtown East · 50 tips and reviews

Libby M.Libby Maxx Power: Gnocchi is excellent! Great wine. Good vibe. Came on a Monday and quite buzzy

Andrew S.Andrew Smallwood: Great for breakfast with a twist

Hailey Heewoo K.Hailey Heewoo Kim: Cute atmosphere, awesome food! The calamari was amazing(!!) and absolutely loved(!!!) the squid ink rigatoni with crab - it had the perfect hint of spice! Looking forward to another visit!