Hotel Biron is one of The 15 Best Places for Wine in San Francisco.

1. Hotel Biron

9.0
45 Rose St (at Market St), San Francisco, CA
Wine Bar · Civic Center · 60 tips and reviews

Carrie N.Carrie Nyden: I found my spot for wine in SF! Their wine list is the best I've seen (great variety & they have wines from one of my favorite importers - Louis Dressner). Amazing date spot too!

Jake L.Jake Lewis: Best intimate wine bar in San Francisco. Best wine selection especially by the bottle

Rachel K.Rachel Kroft: Great wine and an intimate ambiance. Great for a date or getting together with a good friend.

20 Spot is one of The 15 Best Places for Wine in San Francisco.

2. 20 Spot

9.0
3565 20th St (at Lexington St), San Francisco, CA
Wine Bar · Mission District · 60 tips and reviews

Jen G.Jen G: Awesome bread plate and wines! The staff are really knowledgeable and helpful. Awesome date spot as well.

LorcánLorcán: Love the rotating wine flights. The nuts&olives are especially delicious when they have macadamias. Bread plate is generous. Devilled eggs are above average. Food and wine here are lovely all around.

Victoria U.Victoria U.: Great wine bar in the Mission. Couch in the back is great for walk-ins and a nightcap.

K&L Wine Merchants is one of The 15 Best Places for Wine in San Francisco.

3. K&L Wine Merchants

9.4
855 Harrison St (btwn 4th and 5th St), San Francisco, CA
Wine Store · SoMa · 55 tips and reviews

Ricardo V.Ricardo Villarreal: Talk to the staff, they are so knowledgeable about the wines they carry and they have tried them all. They have always given me great wine recommendations.

Chris E.Chris Edwards: Best prices for wine & liquor in the Bay Area and exceptionally helpful staff. You can also order online and pick up in-store.

Sherry L.Sherry Li: I love this wine shop. They have a good variety of wine, spirits, and even a small sake selection. The staff are very nice and helpful if you need suggestions.

Fig & Thistle Wine Bar is one of The 15 Best Places for Wine in San Francisco.

4. Fig & Thistle Wine Bar

8.7
313 Ivy St (at Gough St), San Francisco, CA
Wine Bar · Hayes Valley · 48 tips and reviews

Kyle M.Kyle Minor: Hidden & right-sized wine & beer bar w/ an all domestic menu. Meats & cheeses for snacking. Try the Ploughman's special: a beer, a bit of cheese, some local chutney, & some bread. Simply perfect!

Jaki L.Jaki Levy: Beer, wine, and cheese. Get here around and 5:30 and have your pick of any seat in the house. Cozy and comfy.

Brandon C.Brandon Cain: Very cozy wine bar with great selection. Off the beaten path. Get the wine flight to sample what they have to offer

Birba is one of The 15 Best Places for Wine in San Francisco.

5. Birba

9.4
458 Grove St (btwn Gough & Octavia St), San Francisco, CA
Wine Bar · Hayes Valley · 23 tips and reviews

Arielle Z.Arielle Z: Angela, the owner, is fantastic! Great wine and snacks. Get Jill's cheesecake!

Eugene K.Eugene Kim: Cozy, small wine bar with a friendly staff and a very interesting wine selection (lots from eastern Europe). Good spot to kill time before a music concert nearby.

ChrisTestChrisTest: Amazing wine bar with an outdoor patio in the back. Great food, wine, and service.

Union Larder is one of The 15 Best Places for Wine in San Francisco.

6. Union Larder

9.0
1945 Hyde St (btwn Union & Green), San Francisco, CA
Wine Bar · Russian Hill · 23 tips and reviews

Pal B.Pal Biro: Fantastic wine bar. Caring staff and brilliant wines & food

Raghav G.Raghav Gulati: Solid selection of wine (+more room than the nearby, lovely Bacchus), meat + cheese. The service was very accommodating to our rowdy group.

Alex F.Alex Fitzroy: If you are gluten free and love eating cheese with your wine, come here and ask for the gluten free crackers! (Also they have super friendly staff and a great selection of wine and cheese)

Ruby Wine is one of The 15 Best Places for Wine in San Francisco.

7. Ruby Wine

9.4
1419 18th St (Missouri), San Francisco, CA
Wine Store · Potrero Hill · 18 tips and reviews

Rob F.Rob Finley: Love this wine store! And it's the only one in Portrero. Nice tastings and wines by the glass.

Tony S.Tony Stuck: Awesome place. Very personalized service, super knowledgable, and great selection of wines that most places don't carry. About 25% local wines, the rest sourced from around the world.

Jenny U.Jenny Ung: Lovely, charming, and quaint wine spot and bar. Happy this is in the neighborhood! Go have a glass of wine with a friend or lover for a low key night!

Frances is one of The 15 Best Places for Wine in San Francisco.

8. Frances

9.1
3870 17th St (at Pond St), San Francisco, CA
New American Restaurant · Castro · 157 tips and reviews

Kimberly O.Kimberly Odom: House wine is a steal and the vegetable cassoulet was out of this world!

Andrew C.Andrew Cerda: Stick to the affordable house wine and you can order all of the bouchees and appetizers - they're divine! And if there's a soup, you have to order it! Perello has a knack for soups.

Lynne 🐰 Q.Lynne 🐰 Qu: Beer and wine are amazing! Love the dessert. The duck entree was a bit dry and salty tho.

inoVino is one of The 15 Best Places for Wine in San Francisco.

9. inoVino

8.9
108B Carl St (Cole St.), San Francisco, CA
Wine Bar · Cole Valley · 18 tips and reviews

Damian B.Damian Bayona: Simple, delicious foods to pair with the exquisite wine list. Multiple Nebbiolos for you to try - always a good sign at a wine bar.

nancy t.nancy t.: Great wines, delicious food, and cozy (small) place. Good for dates or intimate get-together.

Catherine S.Catherine Scholz: Cute ambiance and delicious food and wine. Love this place

Heirloom Café is one of The 15 Best Places for Wine in San Francisco.

10. Heirloom Café

9.0
2500 Folsom St (at 21st St), San Francisco, CA
New American Restaurant · Mission District · 69 tips and reviews

Alexandra S.Alexandra Skillman: Great wine selection, my fav olives to start and one of the coolest atmospheres in the city! Culinary delight!

Holger L.Holger Lüdorf: Great wine selection, very fresh California cuisine, and excellent service. Try the Buratta on Asparagus and the stewed mussels.

David N.David Noël: My favorite restaurant in SF. Great taste, fresh local produce, great service and wine selection and the desserts are exquisite. Chef Josh and his team have something special going on there.

flour + water is one of The 15 Best Places for Wine in San Francisco.

11. flour + water

8.9
2401 Harrison St (at 20th St), San Francisco, CA
Italian Restaurant · Mission District · 264 tips and reviews

Corinna P.Corinna P: Great wines and excellent pizza. Be on the lookout for their specials, which are always the standout.

Katherine B.Katherine Barna: Wonderful pasta and pizza and a great selection of Italian wine. Don't miss out on the fennel pollen battered olives filled with ricotta w/ aioli on the side. Whoa.

John D.John Doherty: Just delicious. Great food, great wine, awesome staff, open late.

Quince is one of The 15 Best Places for Wine in San Francisco.

12. Quince

8.9
470 Pacific Ave (at Montgomery St), San Francisco, CA
New American Restaurant · Jackson Square · 77 tips and reviews

Lynnet S.Lynnet Spiegel: This place was fabulous! The variety of cheese is amazing! Great wine list & the food is outstanding! 4 stars!

Sandra P.Sandra Pecis: One of the best restaurants is SFO. The 4 plates menu is awesome. Try the CRUDO, then the Tagliateli, the Duck and the Pear as dessert. Best choice: wine pairing with the tips of the sommelier.

Gabrielle C.Gabrielle Clarke: Glorious and amazing. If you let them know you are celebrating something they take amazingly good care of you! Also the sommelier is one of the best I have experienced. She knows her stuff!!!

Little Vine is one of The 15 Best Places for Wine in San Francisco.

13. Little Vine

8.8
1541 Grant Ave (btwn Filbert & Union St), San Francisco, CA
Gourmet Store · North Beach · 22 tips and reviews

polynesian m.polynesian metal: Pick up a bottle of screwtop wine some artisan chrese, sourdough and salumi and picnic at Coit Tower. The tourists will be all "Why didn't we think of that?"

CJCJ: It's hard to go wrong here w/all of their offerings of wine, sandwiches (spicy turkey is my fav), cheese, olive oil, and the kouign amanns from Oakland's Starter Bakery. Next to do: Wine Club!

H H.H H: Having a picnic in Washington Square Park? Pick up a bottle of wine, your own makings of a charcuterie plate, the sandwich of the day if you're really hungry and you're ready to enjoy the SF sun!

Cafe Meuse is one of The 15 Best Places for Wine in San Francisco.

14. Cafe Meuse

9.0
1400 Pacific Ave (at Hyde St.), San Francisco, CA
Wine Bar · Nob Hill · 20 tips and reviews

Dirk W.Dirk Wilfling: Great place to spend quality time with friends. Ask the waiters for their favorite wines - has always been a great pick!

Jennifer D.Jennifer Darwin: Tuna Tartar is the best! Amazing wine and cheese plates! Great selection of wine to go with everything!

Jennifer D.Jennifer Darwin: Great Tuna Tartar... Wine selection is awesome! Great neighborhood hang out

Spruce is one of The 15 Best Places for Wine in San Francisco.

15. Spruce

8.9
3640 Sacramento St (btwn Spruce & Locust St), San Francisco, CA
New American Restaurant · Presidio Heights · 133 tips and reviews

The Daily MealThe Daily Meal: Wine lovers abound in San Francisco, and the options for indulging in a great local bottle are plenty. Try the food as well--burrata with market cherries, ricotta ravioli, and butter poached lobster. Read more.

astraeaastraea: Burger and fries is an awesome choice and Dylan was a great server!! Awesome wine list. Something for everyone's taste.

LukaLuka: Contemporary American restaurant with a wine list of 2,500 bottles, one Michelin star. Get Kurobuta Pork Loin ($26), it's amazing Read more.