4100 University Ave, Des Moines, IA 50311
Open until 11:59pm (Show more)
  • Mon–Sun
    • 6:00 AM–11:59 PM
Credit Cards:
Yes (incl. American Express)

Come shop with us. Grab a cup of Starbucks or Caribou coffee to enjoy while you pick up your groceries, refill your prescriptions and select a bouquet of flowers. Don’t forget to use your Fuel Saver rewards when filling your tank at your local Hy-Vee Gas station.


Based on 440 votes

People like this place

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11 Tips

People talk about:

  • "Best place to make your own 6 pack. Still $8.99 and best choice of beers." (2 tips)
  • "make your own 6 pack" (2 tips)
  • "Great liquor selection, check out the discount wine cart!" (1 tip)
  • Phil J.

    I go to Hy-Vee Drugstore because of the friendly people who work there. From the Pharmacy to the checkers, they take an active role in customer service.

    Phil J. · April 27, 2010
  • Jeff V.

    make your own 6 pack

    Jeff V. · February 28, 2010
  • Robbie H.

    Best place to make your own 6 pack. Still $8.99 and best choice of beers.

    Robbie H. · March 24, 2012
  • Your Downtown Gal

    Free 20 oz diet pepsi when you check in here!!! Cool

    Your Downtown Gal · September 25, 2011
  • Rose M.

    Great liquor selection, check out the discount wine cart!

    Rose M. · September 19, 2011
  • Deborah P.

    The produce is top notch!!

    Deborah P. · June 5, 2012
  • Tony S.

    I like Hyvee, but I have to say I just had the worst customer service EVER in their building. The curly-headed guy with the glasses in the liquor department can die in a fire, for all I care...

    Tony S. · October 3, 2011
  • Doorstep D.

    Don't forget your green bags, Mother Earth thanks you!

    Doorstep D. · May 12, 2010
  • MOnica Y.

    This is one of the best places to shop for greeting cards

    MOnica Y. · May 11, 2013
  • bob s.

    if your trying to buy booze wine and spirits is open till midnight. store used to be 24/7. not no more.

    bob s. · August 9, 2012
  • Deborah P.

    The produce department is one of the best in the city!

    Deborah P. · April 25, 2012

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Chris P.

Mayor: Chris P.

45 check-ins in the last 60 days

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