Take the bus 119 to the centre. Go left out of the building and go to stop opposite the Travel Service building. Take metroA at the bus terminal for further connection to center.
A nice place near to the airport. The only problem I had, in checking-in the guy who supposed to carry the luggage upstairs wasn't there. So I had to carry them in the cart by myself!
STOP OVER AT THE CONTEMPORARY HOLIDAY INN PRAGUE AIRPORT HOTEL A SHORT SHUTTLE RIDE TO THE AIRPORT TERMINALS AND IN REACH OF PRAGUES OLD TOWN. GLASS ELEVATORS TRANSPORT YOU BETWEEN FLOORS AT THE FUTURISTIC STEELDESIGNED HOLIDAY INN PRAGUE AIRPORT LOCATED ONSITE AT PRAGUE RUZYNE
AIRPORT.