Five Guys is one of The 11 Best Places for Cheeseburgers in South Loop, Chicago.

1. Five Guys

8.2
1146 S Wabash, Chicago, IL
Burger Joint · South Loop · 40 tips and reviews

Gabe Y.Gabe Yocum: Ask them to keep the fries down a little longer. Crispity crunch. Get yourself that double cheeseburger.

Dan C.Dan Craig: I could be addicted to the cheeseburgers. Dangerous. There are lots of toppings, but it's ok to keep it simple.

Maike P.Maike Plotnik: Double cheeseburger with Cajun style fries and a drink with free re-fills- that's all you need!

Epic Burger is one of The 11 Best Places for Cheeseburgers in South Loop, Chicago.

2. Epic Burger

7.4
517 S State St (btwn E Congress Pkwy & E Harrison St), Chicago, IL
Burger Joint · South Loop · 104 tips and reviews

Randy E.Randy Escalada: Cheeseburger with fried egg!

Alexis B.Alexis Budejen: Burger. Cheese burger. Add an egg.

Noah A.Noah Adams: SO good- get the BBQ bacon cheeseburger!

S.R.O. - Standing Room Only is one of The 11 Best Places for Cheeseburgers in South Loop, Chicago.

3. S.R.O. - Standing Room Only

7.7
610 S Dearborn St (at W Harrison St), Chicago, IL
American Restaurant · Printer's Row · 25 tips and reviews

Big M.Big Mark: Bacon Cheeseburger is a GO!!! Fresh, flavorful and that's just the bun lol. Definitely in the top 10 of burger places in Chicago

Roosevelt CollectionRoosevelt Collection: Two burgers worth trying: South Western Black Bean Burger & the SRO Burger - their signature burger. You will NOT regret either choice.

Kevin H.Kevin Higgins: Food is good. Service is not the friendliest. Worth stopping in if you need a bit to eat and are in the area.

Devil Dawgs is one of The 11 Best Places for Cheeseburgers in South Loop, Chicago.

4. Devil Dawgs

7.6
767 S State St (Polk St), Chicago, IL
Hot Dog Joint · Dearborn Park · 47 tips and reviews

BigTab R.BigTab R.N.: Never actually had a dog here but the burgers are about the same size as a Wendy's Jr. Cheeseburger. They're small but absolutely delicious.

Jake L.Jake Lefkovitz: The classic cheeseburger is really good. They also give you plenty of fries

User U.User Unknown: Loved devil dawgs,everyone has to go here! Good prices,good food,fast,quality. Try the morning morning steak burger w avocado on it,it is to die for! Hand-cut fries speak for itself 🍔🍟💕

Buddy Guy's Legends is one of The 11 Best Places for Cheeseburgers in South Loop, Chicago.

5. Buddy Guy's Legends

8.6
700 S Wabash Ave (at Balbo Dr.), Chicago, IL
Music Venue · South Loop · 140 tips and reviews

Mathieu G.Mathieu Gombault: Blues burger is just amazing!!!

Leandro A.Leandro Araujo: Probably the most comfortable live music bar I've ever been... a MUST go if you're in Chicago.

Explore ChicagoExplore Chicago: Local and international legends play here, and Buddy Guy himself graces the stage of his authentic blues club, where memorabilia like B.B. King and John Lee Hooker’s guitars complete the atmosphere. Read more.

The Burger Point is one of The 11 Best Places for Cheeseburgers in South Loop, Chicago.

6. The Burger Point

7.8
1900 S State St (Archer & State), Chicago, IL
Burger Joint · South Loop · 59 tips and reviews

BernadetteBernadette: Mmm crunchy burger!! Cheeseburger with potato chips and French onion dip on top. Delicious!

Roosevelt CollectionRoosevelt Collection: No words describe the burgers here. We love them all. Here are two we recommend trying: The Burger Point Burger & The Hangover. Enjoy!

Time Out ChicagoTime Out Chicago: What no one tells you is that the burgers are de facto cooked to medium-well, and that the signature item—the Burger Point Burger with roasted chili peppers—is hot enough to burn your face off. Read more.

Eleven City Diner is one of The 11 Best Places for Cheeseburgers in South Loop, Chicago.

7. Eleven City Diner

8.9
1112 S Wabash Ave (btwn 11th St & Roosevelt Rd), Chicago, IL
Diner · South Loop · 299 tips and reviews

Brandyn D.Brandyn Dyke: Double double cheeseburger is amazing!

Ken D.Ken Dumas: Awesome South Loop joint well worth any wait time. Egg cream brings back great memories for my wife who grew up in Brooklyn. We love this place!

ElevenEleven: Unlock our special!!!!!!!

Eppel's Restaurant is one of The 11 Best Places for Cheeseburgers in South Loop, Chicago.

8. Eppel's Restaurant

8.0
554 W Roosevelt Rd (Jackson), Chicago, IL
Diner · South Loop · 15 tips and reviews

Tru W.Tru Wish: The staff is amazing very friendly great food one of the best and I dine out alot luv it

RoGina W.RoGina Williams-Montgomery: Best breakfast. Cheap with good portions

Amy M.Amy Marden: The soup is really good!!!!

Burger Bar is one of The 11 Best Places for Cheeseburgers in South Loop, Chicago.

9. Burger Bar

8.2
1150 S Michigan Ave (at E Roosevelt Rd), Chicago, IL
Burger Joint · South Loop · 31 tips and reviews

Shannon L.Shannon Lindell: The sweet potato tatter tots are my favorite. Every burger that I have tried has been excellent. Along with hand mixed shakes. Only caution is the portions are huge!

Lindsay M.Lindsay M: Been here on multiple occasions - great food, however every time I've been here it's taken over 30 minutes to get our food (both when it's busy and not).

Ricel A.Ricel Almadovar: Burger is juicy and flavorful. Calamari is a good appy. Beer selection plentiful. Signs of a good watering hole!!

Little Branch Cafe South Loop is one of The 11 Best Places for Cheeseburgers in South Loop, Chicago.

10. Little Branch Cafe South Loop

7.7
1251 S Prairie Ave (at S. Indiana Ave.), Chicago, IL
American Restaurant · South Loop · 44 tips and reviews

Time Out ChicagoTime Out Chicago: Fluffy cupcakes, both red velvet and buttermilk, along with the brownies, also passed our crew’s taste test. Read more.

Roosevelt CollectionRoosevelt Collection: If you're drinking, get the Sangria. If you're recovering from drinking, try their coffee. Both are fabulous.

StephenStephen: Here for breakfast, but love the turkey reuben.

Noodles & Company is one of The 11 Best Places for Cheeseburgers in South Loop, Chicago.

11. Noodles & Company

7.1
1022 S Canal St, Chicago, IL
Asian Restaurant · South Loop · 5 tips and reviews

ErnestoErnesto: Spicy Chicken Ceasar Sandwich is legit!

Julia KwanJulia Kwan: Add chicken/meatballs to your pasta. I like this place. It's cheap.

Kevin M.Kevin Mac: Pesto Cavatappi