Hotel Biron is one of The 15 Best Places for Wine in San Francisco.

1. Hotel Biron

45 Rose St (at Market St.), San Francisco, CA
Wine Bar · Civic Center · 57 tips and reviews

Peter S.Peter Shanley: Go to Hotel Biron, ask Chris for a recommendation on a nice bottle, get a cheese plate with Blue Cheese/Honey and the Triple Cream, play a game of cribbage and enjoy the best wine bar in SF

erin b.erin butner: Great hidden gem. Good wine list and a delish cheese plate. Take in the rotating art and sip on a glass of wine.

Clara C.Clara Cambon: Check their Facebook page for offers on a selection of wines, a few times a week. Great atmosphere: brick, leather, wood, nice music. Good wine selection and simple but delicious small plates.

20 Spot is one of The 15 Best Places for Wine in San Francisco.

2. 20 Spot

3565 20th St (at Lexington St), San Francisco, CA
Wine Bar · Mission District · 50 tips and reviews

SF WeeklySF Weekly: The wine bar, from owners Bodhi Freedom (owner of Bacchus) and chef Anthony Paone, boasts a list of North American as well as French, Italian and German wines as well as local beer. Read more.

Jen G.Jen G: Awesome bread plate and wines! The staff are really knowledgeable and helpful. Awesome date spot as well.

Pei 👻 W.Pei 👻 Wen: Awesome wine list and dessert. Their dimly lit sofa couch is the best spot to carry out midnight deep conversations with your SO.

K&L Wine Merchants is one of The 15 Best Places for Wine in San Francisco.

3. K&L Wine Merchants

855 Harrison St (btwn 4th and 5th St), San Francisco, CA
Wine Shop · SoMa · 49 tips and reviews

Ricardo V.Ricardo Villarreal: Talk to the staff, they are so knowledgeable about the wines they carry and they have tried them all. They have always given me great wine recommendations.

Miwa N.Miwa Nagamitsu Ahlstrom: My absolute favorite wine shop in SF. Amazing selection of wine from all over!

Chris E.Chris Edwards: Best prices for wine & liquor in the Bay Area and exceptionally helpful staff. You can also order online and pick up in-store.

Fat Angel Food & Libation is one of The 15 Best Places for Wine in San Francisco.

4. Fat Angel Food & Libation

1740 Ofarrell St (at Fillmore St.), San Francisco, CA
Gastropub · Fillmore District · 116 tips and reviews

Gwyn C.Gwyn C: This is definitely one of the best meals in recent memory...we ordered a bottle of prosecco, a cheese plate, the mac & cheese, a flat bread and a huge salad...everything was fabulous!

Ruby A.Ruby Anaya: Awesome and unique beer selection and great draft wines. The sliders are incredible! The salads are REALLY big - think of "The Big Salad" from Seinfeld - but they are all delicious & great to share.

Lauren S.Lauren Strehlow: Huge salads, great flatbread, give me all the beer and wine!

Fig & Thistle Wine Bar is one of The 15 Best Places for Wine in San Francisco.

5. Fig & Thistle Wine Bar

313 Ivy St (Gough), San Francisco, CA
Wine Bar · Hayes Valley · 37 tips and reviews

Kyle M.Kyle Minor: Hidden & right-sized wine & beer bar w/ an all domestic menu. Meats & cheeses for snacking. Try the Ploughman's special: a beer, a bit of cheese, some local chutney, & some bread. Simply perfect!

Jayson P.Jayson Phillips: Great wine bar nestled off the main strip. Suitable for dates and group hangouts

Jaki L.Jaki Levy: Beer, wine, and cheese. Get here around and 5:30 and have your pick of any seat in the house. Cozy and comfy.

Mission Cheese is one of The 15 Best Places for Wine in San Francisco.

6. Mission Cheese

736 Valencia St (at 18th St), San Francisco, CA
Cheese Shop · Mission District · 90 tips and reviews

Tye C.Tye Chait: Wine and cheese pairing! Try the Alotta Burrata sandwich

Ashok L.Ashok Lalwani: Had the California Cheese Flight. Really unique selection and server explained the selection with great detail. The place is really small making it hard to find a table. Great wine pairing too.

Carrie N.Carrie Nyden: Amazing wines and cheeses! The staff is incredibly friendly and helpful too. Definitely reserve a spot for their Night Cheese events!

Arlequin Cafe & Food To Go is one of The 15 Best Places for Wine in San Francisco.

7. Arlequin Cafe & Food To Go

384 Hayes St (at Gough St), San Francisco, CA
Café · Civic Center · 171 tips and reviews

Natasha W.Natasha W: Outside seating plus a bottle of wine from next door makes for a great brunch setting. Five dollar corkage fee for purchased bottles.

Amy W.Amy Widdowson: Great place to grab a light lunch (side of ratatouille is more than enough) and a glass of wine while you work. Lovely staff and yummy munchies.

Liza P.Liza P: Secret garden in Hayes Valley! Get a bottle of wine to share, and a lamb burger and have it all at one of the rickety tables in the garden.

Union Larder is one of The 15 Best Places for Wine in San Francisco.

8. Union Larder

1945 Hyde St (btwn Union & Green), San Francisco, CA
Wine Bar · Russian Hill · 17 tips and reviews

Steve K.Steve Kirkham: Great new wine bar on Hyde. Several wines on tap, solid cheese selection, and a collection of hot appetizers. Grab a spot along the windows for fresh air and people watching!

Pal B.Pal Biro: Fantastic wine bar. Caring staff and brilliant wines & food

Vic A.Vic Avery: Good selection of wine, tasty food, good variety of cheese... Friendly & competent staff. It's one of the very few places that has decent bresaola!

High Treason is one of The 15 Best Places for Wine in San Francisco.

9. High Treason

443 Clement, San Francisco, CA
Wine Bar · Inner Richmond · 13 tips and reviews

Will B.Will Bertelsen: Nice, knowledgable staff pours interesting wines by the glass and plays cool records!

Kenfe-Mickaël L.Kenfe-Mickaël LAVENTURE: Wine is lovely, John is an awesome host and very knowledgeable about his wine. Food is good too

Dr x.Dr x: Giant and varied list of wines by the glass, super friendly and non-intimidating servers and owners, fabulous space.

Frances is one of The 15 Best Places for Wine in San Francisco.

10. Frances

3870 17th St (at Pond St), San Francisco, CA
New American Restaurant · Castro · 147 tips and reviews

Catherine B.Catherine B.: Try the house wine; it is always great and you are only charged for what you drink!

Kimberly O.Kimberly Odom: House wine is a steal and the vegetable cassoulet was out of this world!

Andrew C.Andrew Cerda: Stick to the affordable house wine and you can order all of the bouchees and appetizers - they're divine! And if there's a soup, you have to order it! Perello has a knack for soups.

Nectar Wine Lounge is one of The 15 Best Places for Wine in San Francisco.

11. Nectar Wine Lounge

3330 Steiner (btw Lombard and Chestnut), San Francisco, CA
Wine Bar · Marina District · 22 tips and reviews

Maribel L.Maribel Lopez: Great half priced wine list for happy hour in SF. Starts at 5:30 ends at 7. Read more.

Brett D.Brett DeFevere: Great weekly specials, presently enjoying Mondays 1/2 off cellar Wine deal. Pick something fancy!!!

Oscar L.Oscar L: Cheese platter is really good. Great wine and super friendly service.

Heirloom Café is one of The 15 Best Places for Wine in San Francisco.

12. Heirloom Café

2500 Folsom St (at 21st St), San Francisco, CA
Italian Restaurant · Mission District · 62 tips and reviews

Alexandra S.Alexandra Skillman: Great wine selection, my fav olives to start and one of the coolest atmospheres in the city! Culinary delight!

Holger L.Holger Luedorf: Great wine selection, very fresh California cuisine, and excellent service. Try the Buratta on Asparagus and the stewed mussels.

Chris M.Chris Messina: Brilliant wine selection. Everything is good; you can't go wrong.

flour + water is one of The 15 Best Places for Wine in San Francisco.

13. flour + water

2401 Harrison St (at 20th St), San Francisco, CA
Italian Restaurant · Mission District · 235 tips and reviews

Sweet N.Sweet Nicouze: Excellent food by chef Thomas McNauighton and effective and friendly service at this italian foodie place in Mission. Good Italian wine selection and excellent pork-based dishes.

Katherine M.Katherine M.: Best freshly made pasta. Excellent pasta tasting and wine pairing menus. Good for a special occasion but pretty affordable. Make a reservation or be prepared to put your name down and come back later.

Katherine B.Katherine Barna: Wonderful pasta and pizza and a great selection of Italian wine. Don't miss out on the fennel pollen battered olives filled with ricotta w/ aioli on the side. Whoa.

Ruby Wine is one of The 15 Best Places for Wine in San Francisco.

14. Ruby Wine

1419 18th St (Missouri), San Francisco, CA
Wine Shop · Potrero Hill · 12 tips and reviews

Tony S.Tony Stuck: Awesome place. Very personalized service, super knowledgable, and great selection of wines that most places don't carry. About 25% local wines, the rest sourced from around the world.

Carrie N.Carrie Nyden: Best wine shop in San Francisco. Lots of great natural wines and everyone is super helpful in terms of picking out which wine to buy! Plus they do daily tastings!

Jenny U.Jenny Ung: Lovely, charming, and quaint wine spot and bar. Happy this is in the neighborhood! Go have a glass of wine with a friend or lover for a low key night!

Birba is one of The 15 Best Places for Wine in San Francisco.

15. Birba

458 Grove St, San Francisco, CA
Wine Bar · Hayes Valley · 12 tips and reviews

Arielle Z.Arielle Z: Angela, the owner, is fantastic! Great wine and snacks. Get Jill's cheesecake!

Stephen G.Stephen Garcia: Amazing wine selection!

Robert M.Robert McKinley: Spectacular wine list and great food with a smart owner that is always there to make sure I'm happy.