Hotel Biron is one of The 15 Best Places for Wine in San Francisco.

1. Hotel Biron

45 Rose St (at Market St.), San Francisco, CA
Wine Bar · Civic Center · 56 tips and reviews

Peter S.Peter Shanley: Go to Hotel Biron, ask Chris for a recommendation on a nice bottle, get a cheese plate with Blue Cheese/Honey and the Triple Cream, play a game of cribbage and enjoy the best wine bar in SF

erin b.erin butner: Great hidden gem. Good wine list and a delish cheese plate. Take in the rotating art and sip on a glass of wine.

Bre L.Bre Lambert: Vibe is romantic & secretive. Get the full spread–cheese, meat, fruit, olives & chocolate-to pair with your wine. Tuck into the back room for privacy, but take note that's also where bathrooms are.

20 Spot is one of The 15 Best Places for Wine in San Francisco.

2. 20 Spot

3565 20th St (at Lexington St), San Francisco, CA
Wine Bar · Mission District · 48 tips and reviews

SF WeeklySF Weekly: The wine bar, from owners Bodhi Freedom (owner of Bacchus) and chef Anthony Paone, boasts a list of North American as well as French, Italian and German wines as well as local beer. Read more.

Pei 👻 W.Pei 👻 Wen: Awesome wine list and dessert. Their dimly lit sofa couch is the best spot to carry out midnight deep conversations with your SO.

LorcánLorcán: Love the rotating wine flights. The nuts&olives are especially delicious when they have macadamias. Bread plate is generous. Devilled eggs are above average. Food and wine here are lovely all around.

K&L Wine Merchants is one of The 15 Best Places for Wine in San Francisco.

3. K&L Wine Merchants

855 Harrison St (btwn 4th and 5th St), San Francisco, CA
Wine Shop · SoMa · 48 tips and reviews

Ricardo V.Ricardo Villarreal: Talk to the staff, they are so knowledgeable about the wines they carry and they have tried them all. They have always given me great wine recommendations.

Miwa N.Miwa Nagamitsu Ahlstrom: My absolute favorite wine shop in SF. Amazing selection of wine from all over!

Sherry L.Sherry Li: I love this wine shop. They have a good variety of wine, spirits, and even a small sake selection. The staff are very nice and helpful if you need suggestions.

Fat Angel Food & Libation is one of The 15 Best Places for Wine in San Francisco.

4. Fat Angel Food & Libation

1740 Ofarrell St (at Fillmore St.), San Francisco, CA
Gastropub · Fillmore District · 117 tips and reviews

Gwyn C.Gwyn C: This is definitely one of the best meals in recent memory...we ordered a bottle of prosecco, a cheese plate, the mac & cheese, a flat bread and a huge salad...everything was fabulous!

AskMenAskMen: With about a half dozen wines on tap -- literally: your wine comes from a pressurized barreL - & a nice snacks menu of meats, cheese & sliders, packing on a few more pounds has never felt so heavenly. Read more.

Tyler H.Tyler Hedrick: Sliders, cask wine, and the Mac and cheese are all good!

Fig & Thistle Wine Bar is one of The 15 Best Places for Wine in San Francisco.

5. Fig & Thistle Wine Bar

313 Ivy St (Gough), San Francisco, CA
Wine Bar · Hayes Valley · 36 tips and reviews

Stefanie S.Stefanie Sundby: Really laid back, great vibe for a wine bar. Table might be hard to find after 9 or 10pm

Kyle M.Kyle Minor: Hidden & right-sized wine & beer bar w/ an all domestic menu. Meats & cheeses for snacking. Try the Ploughman's special: a beer, a bit of cheese, some local chutney, & some bread. Simply perfect!

Peter T.Peter T: cozy & a nice wine list

Mission Cheese is one of The 15 Best Places for Wine in San Francisco.

6. Mission Cheese

736 Valencia St (at 18th St), San Francisco, CA
Cheese Shop · Mission District · 86 tips and reviews

Jared N.Jared Nusinoff: amazing wine goes well with mongers cheese.... but the BEST thing was the duck liver paté!

Tye C.Tye Chait: Wine and cheese pairing! Try the Alotta Burrata sandwich

Ashok L.Ashok Lalwani: Had the California Cheese Flight. Really unique selection and server explained the selection with great detail. The place is really small making it hard to find a table. Great wine pairing too.

Arlequin Cafe & Food To Go is one of The 15 Best Places for Wine in San Francisco.

7. Arlequin Cafe & Food To Go

384 Hayes St (at Gough St), San Francisco, CA
Café · Civic Center · 163 tips and reviews

Natasha W.Natasha W: Outside seating plus a bottle of wine from next door makes for a great brunch setting. Five dollar corkage fee for purchased bottles.

Amy W.Amy Widdowson: Great place to grab a light lunch (side of ratatouille is more than enough) and a glass of wine while you work. Lovely staff and yummy munchies.

Sherry L.Sherry Li: Love the outdoor area here. Great wine selection too.

Union Larder is one of The 15 Best Places for Wine in San Francisco.

8. Union Larder

1945 Hyde St (btwn Union & Green), San Francisco, CA
Wine Bar · Russian Hill · 15 tips and reviews

Steve K.Steve Kirkham: Great new wine bar on Hyde. Several wines on tap, solid cheese selection, and a collection of hot appetizers. Grab a spot along the windows for fresh air and people watching!

Pal B.Pal Biro: Fantastic wine bar. Caring staff and brilliant wines & food

Vic A.Vic Avery: Good selection of wine, tasty food, good variety of cheese... Friendly & competent staff. It's one of the very few places that has decent bresaola!

Sundance Kabuki Cinemas is one of The 15 Best Places for Wine in San Francisco.

9. Sundance Kabuki Cinemas

1881 Post St (at Fillmore St), San Francisco, CA
Movie Theater · Japantown · 247 tips and reviews

RenoReno: Like Mario says "sneak in either a bottle of champagne tucked in back of trousers, bottle of whiskey (mix with diet coke) and a carton of bbq chow mein' - also good to do at the Castro theatre

Kimberly H.Kimberly Howard: Balcony 1 is the best - bring your wine and popcorn with REAL butter with you

Gillian M.Gillian M.: Best tots. Ever. Grab some wine & tots and take it in for a delightful movie experience

SPQR is one of The 15 Best Places for Wine in San Francisco.

10. SPQR

1911 Fillmore St (btwn Bush & Pine), San Francisco, CA
Italian Restaurant · Lower Pacific Heights · 154 tips and reviews

Brian B.Brian Ball: Opt for the wine pairing, it's well worth it!

Jeff T.Jeff Tobias: Perfect assault on your taste buds!! Chicken Liver Pate is a must along with the wine pairings.

Brad T.Brad T: Holy cow! Fantastic everything. Food, service and old world wine selection all great. Order up anything. It won't disappoint.

Frances is one of The 15 Best Places for Wine in San Francisco.

11. Frances

3870 17th St (at Pond St), San Francisco, CA
New American Restaurant · Castro · 145 tips and reviews

timoni w.timoni west: Go with a tiny group, or by yourself, and sit at the bar, order wine, and those frites (!). If you want to go with a larger group, go very late on a weekday, or make a reservation.

Kimberly O.Kimberly Odom: House wine is a steal and the vegetable cassoulet was out of this world!

Andrew C.Andrew Cerda: Stick to the affordable house wine and you can order all of the bouchees and appetizers - they're divine! And if there's a soup, you have to order it! Perello has a knack for soups.

Yield Wine Bar is one of The 15 Best Places for Wine in San Francisco.

12. Yield Wine Bar

2490 3rd St (at 22nd St), San Francisco, CA
Wine Bar · Dogpatch · 28 tips and reviews

Vida H.Vida Ha: Order the Cod Cakes and any of the wine - it's all great!

Angela D.Angela D'Arcy: Amazing wine selection. Interesting & delicious small plates. Great ambiance.

Emily L.Emily Limon: One of my favorite wine bars in the city. All organic, they have some interesting picks. AND the food is nice.

The Social Study is one of The 15 Best Places for Wine in San Francisco.

13. The Social Study

1795 Geary Blvd (Fillmore), San Francisco, CA
Lounge · Fillmore District · 76 tips and reviews

Megan S.Megan Skye: Japanese inspired study bar. Coffee and tea alongside tasty looking beer, wine, and sake.

John D.John Doherty: Good wine list cool atmosphere.

Elizabeth A.Elizabeth Agnew: Very inventive and delicious beer and wine mocktails.

Heirloom Café is one of The 15 Best Places for Wine in San Francisco.

14. Heirloom Café

2500 Folsom St (at 21st St), San Francisco, CA
Italian Restaurant · Mission District · 62 tips and reviews

Oka T.Oka Tai-Lee: wine list has 20 superb wines by the glass, and there's a noteworthy cellar list available by request

Alexandra S.Alexandra Skillman: Great wine selection, my fav olives to start and one of the coolest atmospheres in the city! Culinary delight!

Holger L.Holger Luedorf: Great wine selection, very fresh California cuisine, and excellent service. Try the Buratta on Asparagus and the stewed mussels.

Ruby Wine is one of The 15 Best Places for Wine in San Francisco.

15. Ruby Wine

1419 18th St (Missouri), San Francisco, CA
Wine Shop · Potrero Hill · 12 tips and reviews

Tony S.Tony Stuck: Awesome place. Very personalized service, super knowledgable, and great selection of wines that most places don't carry. About 25% local wines, the rest sourced from around the world.

Carrie N.Carrie Nyden: Best wine shop in San Francisco. Lots of great natural wines and everyone is super helpful in terms of picking out which wine to buy! Plus they do daily tastings!

Jenny U.Jenny Ung: Lovely, charming, and quaint wine spot and bar. Happy this is in the neighborhood! Go have a glass of wine with a friend or lover for a low key night!