Hotel Biron is one of The 15 Best Places for Wine in San Francisco.

1. Hotel Biron

45 Rose St (at Market St.), San Francisco, CA
Wine Bar · Civic Center · 57 tips and reviews

Peter S.Peter Shanley: Go to Hotel Biron, ask Chris for a recommendation on a nice bottle, get a cheese plate with Blue Cheese/Honey and the Triple Cream, play a game of cribbage and enjoy the best wine bar in SF

Nancy C.Nancy Cole: Great little hideaway, down-to-earth wine bar (they have beer too). Perfect for the wine hippies & bohemians who don't want the high-end District / Press Club scene. Good prices, curated selection.

Clara C.Clara Cambon: Check their Facebook page for offers on a selection of wines, a few times a week. Great atmosphere: brick, leather, wood, nice music. Good wine selection and simple but delicious small plates.

20 Spot is one of The 15 Best Places for Wine in San Francisco.

2. 20 Spot

3565 20th St (at Lexington St), San Francisco, CA
Wine Bar · Mission District · 52 tips and reviews

SF WeeklySF Weekly: The wine bar, from owners Bodhi Freedom (owner of Bacchus) and chef Anthony Paone, boasts a list of North American as well as French, Italian and German wines as well as local beer. Read more.

Gina P.Gina P: Out server Aaron was a blast! Cheese plates are awesome and they have a nice selection of wines. Open late on Sundays (till midnight).

Jen G.Jen G: Awesome bread plate and wines! The staff are really knowledgeable and helpful. Awesome date spot as well.

Fig & Thistle Wine Bar is one of The 15 Best Places for Wine in San Francisco.

3. Fig & Thistle Wine Bar

313 Ivy St (Gough), San Francisco, CA
Wine Bar · Hayes Valley · 41 tips and reviews

Kyle M.Kyle Minor: Hidden & right-sized wine & beer bar w/ an all domestic menu. Meats & cheeses for snacking. Try the Ploughman's special: a beer, a bit of cheese, some local chutney, & some bread. Simply perfect!

Jayson P.Jayson Phillips: Great wine bar nestled off the main strip. Suitable for dates and group hangouts

Brandon C.Brandon Cain: Very cozy wine bar with great selection. Off the beaten path. Get the wine flight to sample what they have to offer

K&L Wine Merchants is one of The 15 Best Places for Wine in San Francisco.

4. K&L Wine Merchants

855 Harrison St (btwn 4th and 5th St), San Francisco, CA
Wine Shop · SoMa · 49 tips and reviews

Ricardo V.Ricardo Villarreal: Talk to the staff, they are so knowledgeable about the wines they carry and they have tried them all. They have always given me great wine recommendations.

Sherry L.Sherry Li: I love this wine shop. They have a good variety of wine, spirits, and even a small sake selection. The staff are very nice and helpful if you need suggestions.

Melon L.Melon L: Best selection on wine in SF. One of the only places that carries Bedrock.

Fat Angel Food & Libation is one of The 15 Best Places for Wine in San Francisco.

5. Fat Angel Food & Libation

1740 Ofarrell St (at Fillmore St.), San Francisco, CA
Gastropub · Fillmore District · 120 tips and reviews

Gwyn C.Gwyn C: This is definitely one of the best meals in recent memory...we ordered a bottle of prosecco, a cheese plate, the mac & cheese, a flat bread and a huge salad...everything was fabulous!

AskMenAskMen: With about a half dozen wines on tap -- literally: your wine comes from a pressurized barreL - & a nice snacks menu of meats, cheese & sliders, packing on a few more pounds has never felt so heavenly. Read more.

Lauren S.Lauren Strehlow: Huge salads, great flatbread, give me all the beer and wine!

Mission Cheese is one of The 15 Best Places for Wine in San Francisco.

6. Mission Cheese

736 Valencia St (at 18th St), San Francisco, CA
Cheese Shop · Mission Dolores · 92 tips and reviews

Tye C.Tye Chait: Wine and cheese pairing! Try the Alotta Burrata sandwich

Ashok L.Ashok Lalwani: Had the California Cheese Flight. Really unique selection and server explained the selection with great detail. The place is really small making it hard to find a table. Great wine pairing too.

Carrie N.Carrie Nyden: Amazing wines and cheeses! The staff is incredibly friendly and helpful too. Definitely reserve a spot for their Night Cheese events!

Union Larder is one of The 15 Best Places for Wine in San Francisco.

7. Union Larder

1945 Hyde St (btwn Union & Green), San Francisco, CA
Wine Bar · Russian Hill · 19 tips and reviews

Steve K.Steve Kirkham: Great new wine bar on Hyde. Several wines on tap, solid cheese selection, and a collection of hot appetizers. Grab a spot along the windows for fresh air and people watching!

Pal B.Pal Biro: Fantastic wine bar. Caring staff and brilliant wines & food

Raghav G.Raghav Gulati: Solid selection of wine (+more room than the nearby, lovely Bacchus), meat + cheese. The service was very accommodating to our rowdy group.

Arlequin Cafe & Food To Go is one of The 15 Best Places for Wine in San Francisco.

8. Arlequin Cafe & Food To Go

384 Hayes St (at Gough St), San Francisco, CA
Café · Civic Center · 179 tips and reviews

Natasha W.Natasha W: Outside seating plus a bottle of wine from next door makes for a great brunch setting. Five dollar corkage fee for purchased bottles.

Amy W.Amy Widdowson: Great place to grab a light lunch (side of ratatouille is more than enough) and a glass of wine while you work. Lovely staff and yummy munchies.

Sherry L.Sherry Li: Love the outdoor area here. Great wine selection too.

Frances is one of The 15 Best Places for Wine in San Francisco.

9. Frances

3870 17th St (at Pond St), San Francisco, CA
New American Restaurant · Castro · 153 tips and reviews

Catherine B.Catherine B.: Try the house wine; it is always great and you are only charged for what you drink!

Andrew C.Andrew Cerda: Stick to the affordable house wine and you can order all of the bouchees and appetizers - they're divine! And if there's a soup, you have to order it! Perello has a knack for soups.

Lynne 🐰 Q.Lynne 🐰 Qu: Beer and wine are amazing! Love the dessert. The duck entree was a bit dry and salty tho.

Heirloom Café is one of The 15 Best Places for Wine in San Francisco.

10. Heirloom Café

2500 Folsom St (at 21st St), San Francisco, CA
Italian Restaurant · Mission District · 64 tips and reviews

Alexandra S.Alexandra Skillman: Great wine selection, my fav olives to start and one of the coolest atmospheres in the city! Culinary delight!

Holger L.Holger Luedorf: Great wine selection, very fresh California cuisine, and excellent service. Try the Buratta on Asparagus and the stewed mussels.

Chris M.Chris Messina: Brilliant wine selection. Everything is good; you can't go wrong.

Ruby Wine is one of The 15 Best Places for Wine in San Francisco.

11. Ruby Wine

1419 18th St (Missouri), San Francisco, CA
Wine Shop · Potrero Hill · 13 tips and reviews

Rob F.Rob Finley: Love this wine store! And it's the only one in Portrero. Nice tastings and wines by the glass.

Tony S.Tony Stuck: Awesome place. Very personalized service, super knowledgable, and great selection of wines that most places don't carry. About 25% local wines, the rest sourced from around the world.

Carrie N.Carrie Nyden: Best wine shop in San Francisco. Lots of great natural wines and everyone is super helpful in terms of picking out which wine to buy! Plus they do daily tastings!

Birba is one of The 15 Best Places for Wine in San Francisco.

12. Birba

458 Grove St (btwn Gough & Octavia St), San Francisco, CA
Wine Bar · Hayes Valley · 13 tips and reviews

Arielle Z.Arielle Z: Angela, the owner, is fantastic! Great wine and snacks. Get Jill's cheesecake!

Robert M.Robert McKinley: Spectacular wine list and great food with a smart owner that is always there to make sure I'm happy.

Ben B.Ben Barclay: Cozy neighborhood bar with a great curated selection of wines.

flour + water is one of The 15 Best Places for Wine in San Francisco.

13. flour + water

2401 Harrison St (at 20th St), San Francisco, CA
Italian Restaurant · Mission District · 241 tips and reviews

Approach GuidesApproach Guides: Great wine list. Opt for Le Terrazze's big, fruity Rosso Conero (based on montepulciano grape); if you want a lighter wine, with brighter acidity, try Enfer d’Arvier (based on the petit rouge grape).

Katherine M.Katherine M.: Best freshly made pasta. Excellent pasta tasting and wine pairing menus. Good for a special occasion but pretty affordable. Make a reservation or be prepared to put your name down and come back later.

Katherine B.Katherine Barna: Wonderful pasta and pizza and a great selection of Italian wine. Don't miss out on the fennel pollen battered olives filled with ricotta w/ aioli on the side. Whoa.

Quince is one of The 15 Best Places for Wine in San Francisco.

14. Quince

470 Pacific Ave (at Montgomery St), San Francisco, CA
New American Restaurant · Jackson Square · 74 tips and reviews

Lynnet S.Lynnet Spiegel: This place was fabulous! The variety of cheese is amazing! Great wine list & the food is outstanding! 4 stars!

Sandra P.Sandra Pecis: One of the best restaurants is SFO. The 4 plates menu is awesome. Try the CRUDO, then the Tagliateli, the Duck and the Pear as dessert. Best choice: wine pairing with the tips of the sommelier.

Gabrielle C.Gabrielle Clarke: Glorious and amazing. If you let them know you are celebrating something they take amazingly good care of you! Also the sommelier is one of the best I have experienced. She knows her stuff!!!

Californios is one of The 15 Best Places for Wine in San Francisco.

15. Californios

3115 22nd St (btwn Capp St & S Van Ness Ave), San Francisco, CA
Mexican Restaurant · Mission District · 33 tips and reviews

SFistSFist: Brand new Mission restaurant Californios is a truly tucked-away, romantic little spot that could end up being a runaway hit. It boasts a eight course prix fixe option and some excellent wine pairings. Read more.

LinLin: Amazing tasting menu and wine pairing. Great chef, sous, and staff. Best meal I've had in SF for a long time.

Christine L.Christine Louie: Get the wine pairing. Not only is it a steal, it really is spectacular and will elevate your meal.